Document Details

Document Type : Article In Journal 
Document Title :
A Janus-paper PDMS platform for air-liquid interface cell culture applications
A Janus-paper PDMS platform for air-liquid interface cell culture applications
 
Subject : physics 
Document Language : English 
Abstract : A commercially available Janus paper with one hydrophobic (polyethylene-coated) face and a hygroscopic/hydrophilic one is irreversibly bonded to a polydimethylsiloxane (PDMS) substrate incorporating microfluidic channels via corona discharge surface treatment. The bond strength between the polymer-coated side and PDMS is characterized as a function of corona treatment time and annealing temperature/time. A maximum strength of 392 kPa is obtained with a 2 min corona treatment followed by 60 min of annealing at 120 degrees C. The water contact angle of the corona-treated polymer side decreases with increased discharge duration from 98 degrees to 22 degrees. The hygroscopic/hydrophilic side is seeded with human lung fibroblast cells encapsulated in a methacrylated gelatin (GelMA) hydrogel to show the potential of this technology for nutrient and chemical delivery in an air-liquid interface cell culture. 
ISSN : 0960-1317 
Journal Name : JOURNAL OF MICROMECHANICS AND MICROENGINEERING 
Volume : 25 
Issue Number : 5 
Publishing Year : 1435 AH
2015 AD 
Article Type : Article 
Added Date : Monday, August 21, 2017 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
R RahimiRahimi, R InvestigatorDoctorate 
M Ochoa,Ochoa,, M ResearcherDoctorate 
A DonaldsonDonaldson, A ResearcherDoctorate 
T ParupudiParupudi, T ResearcherDoctorate 
M.R (Dokmeci(Dokmeci, M.R ResearcherDoctorate 
A KhademhosseiniKhademhosseini, A ResearcherDoctorate 
A GhaemmaghamGhaemmagham, A ResearcherDoctorate 
B ZiaieZiaie, B ResearcherDoctoratebziaie@purdue.edu

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