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Document Details
Document Type
:
Article In Journal
Document Title
:
The Role of the Epigenome in Gene Expression Control and the Epimark Changes in Response to the Environment
The Role of the Epigenome in Gene Expression Control and the Epimark Changes in Response to the Environment
Document Language
:
English
Abstract
:
Our knowledge base involving the biochemical participants of epigenetic control has expanded greatly over the last decade. The role of epigenetic marks to DNA and histones controlled by non-coding RNAs is one of the most intensely studied areas of biology today. This review covers many of themechanisms that non-coding RNAs and other molecules use to control gene expression and eventually affect responses to the environment. In the first part of the review, we discuss the array of covalent modifications to the genome that constitute the epigenome, which consists of the histone variants, covalent modifications, and post-translational modifications that result in gene expression changes. How the histone variants and post-translationalmodifications including, acetylation, methylation, phosphorylation, ubiquitination and sumoylation help form the epigenome is also summarized. Our eventual understanding of how the environment controls these modifications will open incredible opportunities in agriculture, medicine and the development of practical tools for biology. In the second part of this review we discuss the growing list of environmentally-mediated epigenetic-modifications, and examples of transgenerational epigenetic inheritance events, that may begin to change our views of adaptive responses to the environment and evolution.
ISSN
:
0735-2689
Journal Name
:
CRITICAL REVIEWS IN PLANT SCIENCES
Volume
:
33
Issue Number
:
1
Publishing Year
:
1435 AH
2014 AD
Article Type
:
Article
Added Date
:
Monday, July 31, 2017
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
Michael Van Oosten
Van Oosten, Michael
Researcher
Ray Bressan
Bressan, Ray
Researcher
Jian-Kang Zhu
Zhu, Jian-Kang
Researcher
Hans Bohnert
Bohnert, Hans
Researcher
Viswanathan Chinnusamy
Chinnusamy, Viswanathan
Researcher
Files
File Name
Type
Description
42358.pdf
pdf
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