Document Details

Document Type : Article In Journal 
Document Title :
Synthesis of Novel Schiff Bases by Microwave Irradiation and Their in vitro Antibacterial Activity
Synthesis of Novel Schiff Bases by Microwave Irradiation and Their in vitro Antibacterial Activity
 
Document Language : English 
Abstract : A series of thiophene-3-carbonitrile contaning schiff bases were synthesized, characterized by the reaction of 2-amino-4,5,6,7-tetrahydro-benzo[b] thiophene-3-carbonitrile and corresponding active aldehyde under microwave irradiation and screened for their antibacterial activities. The structure of synthesized compounds were established by spectroscopic (FT-IR, H-1 NMR, C-13 NMR, Mass) and elemental analyses. The antibacterial activity of these compounds were first tested in vitro by the disk diffusion assay against two Gram-positive and two Gram-negative bacteria and then the minimum inhibitory concentration was determined with the reference of standard drug chloramphenicol. The results showed that compound 6 is better at inhibiting the growth as compared to chloramphenicol against both types of the bacteria (gram-positive and gram-negative). 
ISSN : 0970-7077 
Journal Name : ASIAN JOURNAL OF CHEMISTRY 
Volume : 25 
Issue Number : 15 
Publishing Year : 1434 AH
2013 AD 
Article Type : Article 
Added Date : Wednesday, July 19, 2017 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
S KhanKhan, S Researcher  
A AsiriAsiri, A Researcher  
A KhanKhan, A Researcher  
K KhanKhan, K Researcher  
A ZayedZayed, A Researcher  

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