Document Details

Document Type : Article In Journal 
Document Title :
Spectroscopic studies on the interaction of cilostazole with iodine and 2,3-dichloro-5,6-dicyanobenzoquinone
Spectroscopic studies on the interaction of cilostazole with iodine and 2,3-dichloro-5,6-dicyanobenzoquinone
 
Subject : Chemistry 
Document Language : English 
Abstract : The electron accepting properties of the 2,3-dichloro-5,6- dicyanobenzoquinone and iodine and electron donating properties of the drug cilostazole have been studied using the UV-vis, FT-IR, GC-MS and Far-IR techniques. The interaction of cilostazole drug with iodine and 2,3-dichloro-5,6-dicyanobenzoquinone resulted via the initial formation of charge-transfer complex as an intermediate. The rate of formation of the product have been measured and discussed as a function of solvent and temperature. The complexes have been found by Job's method of continuous variation revealed that the stoichiometry of the complexes in both the cases was 1:1. The enthalpies and entropies of formation of the complexes have been obtained by determining their rate constant at three different temperature. The ionization potential of the donor was determined using the charge-transfer absorption bands of the complexes and the same was found comparable with that computed using MOPAC PM3 method. 
ISSN : 1386-1425 
Journal Name : Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy 
Volume : 78 
Issue Number : 1 
Publishing Year : 1432 AH
2011 AD 
Article Type : Article 
Added Date : Saturday, February 11, 2012 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
M PandeeswaranPandeeswaran, M ResearcherDoctorate 
السيد حسيني المسلميEl-Mossalamy, El-sayed HResearcherDoctoratesbdmina@yahoo.com
K P ElangoElango, K PResearcherDoctoratedrkpelango@rediffmail.com

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