Document Details

Document Type : Article In Journal 
Document Title :
Cysteine- Mediated Excitotoxic Neuronal Death is an Apoptosis- Necrosis Continuum
Cysteine- Mediated Excitotoxic Neuronal Death is an Apoptosis- Necrosis Continuum
 
Subject : Cysteine- Mediated Excitotoxic Neuronal Death is an Apoptosis- Necrosis Continuum 
Document Language : English 
Abstract : To explore the mechanism whereby cysteine induces cell death this study was undertaken using a human medulloblastoma cell-line as the model system. Low levels of cysteine induced several well described phenomena associated with apoptosis, phospatidyl serine exposure,mitochandorial membrane disruption, cleavage of DNA into 50 Kb fragments and induction of caspase 3, whereas higher concentrations tended to cause necrosis. We have speculated on the role of cysteine in the role of cysteine in excitotoxicity, which occurs clinically following cerebral ischemia. 
ISSN : 0971-2119 
Journal Name : J.Appl.Anim.Res 
Volume : 32 
Issue Number : 1 
Publishing Year : 1428 AH
2007 AD 
Number Of Pages : 15 
Article Type : Article 
Added Date : Friday, July 3, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
S. Y.S. Y.InvestigatorDoctorate 
R. B.R. B.ResearcherDoctorate 
R.H.R.H.ResearcherDoctorate 

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