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Document Type |
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Article In Journal |
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Document Title |
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Synthesis of N-1-substituted, N-3[P-(3-ethoxycarbonyl-4,5-dihydronaphtho[1,2-c]pyrazol-2-yl)benzenesulfonyl]urea and thiourea derivatives. Class of cyclooxygenase-2 inhibitors Synthesis of N-1-substituted, N-3[P-(3-ethoxycarbonyl-4,5-dihydronaphtho[1,2-c]pyrazol-2-yl)benzenesulfonyl]urea and thiourea derivatives. Class of cyclooxygenase-2 inhibitors |
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Document Language |
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Arabic |
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Abstract |
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Abstract: Several urea and thiourea derivatives (2a-f) were prepared by the reaction of dihydronaphthopyrazolylbenzenesulfonamide (1) with the corresponding isocyanates and isothiocyanates, respectively. The benzene-sulfonylthioureas (2d,e) were cyclized with ethyl bromoacetate, ethyl beta-bromopropionate and alpha-bromoacetophenones to give the corresponding 4-oxothiazolidine (3a,b), 4-oxo-5,6-dihydrothiazine (4a,b) and thiazoline derivatives (5a-d) respectively. |
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Journal Name |
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Source: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS |
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Volume |
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177 |
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Issue Number |
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3 |
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Publishing Year |
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2002 AH
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Added Date |
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Saturday, June 14, 2008 |
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Researchers
| سالم أحمد باسيف | Basaif SA, | Researcher | | |
| . | Faidallah HM | Researcher | | |
| . | Sharshira EM | Researcher | | |
| . | A-Ba-Oum AE | Researcher | | |
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