Document Details
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Document Type |
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Article In Journal |
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Document Title |
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Synthesis, Spectroscopic Studies of Fluorinated Pyrimido-1,2,4-Triazines: Protective Effect Against Some Plant Pathogenic Fungi Synthesis, Spectroscopic Studies of Fluorinated Pyrimido-1,2,4-Triazines: Protective Effect Against Some Plant Pathogenic Fungi |
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Document Language |
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English |
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Abstract |
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In search for new biologically active compounds, several new fluorine-substituted pyrimido [2,3-c][1,2,4]triazino (3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16) have been synthesized via the nucleophilic attack of 2-hydrazinopyrimidinone (2) toward more positive carbons under different conditions. Structure of the newly synthesized compounds was deduced from elemental analyses as well as their spectral data (UV, IR, NMR, and M/S). The antifungal activity of the target ring systems has been evaluated both in vitro and in vivo against some phytopathogenic fungi associated with wheat grains. Result showed that compounds 6, 7, and 8 have high protection of wheat grains against the fungal infection. |
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ISSN |
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0022-152X |
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Journal Name |
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JOURNAL OF HETEROCYCLIC CHEMISTRY |
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Volume |
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53 |
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Issue Number |
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4 |
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Publishing Year |
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1437 AH
2016 AD |
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Article Type |
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Article |
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Added Date |
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Monday, August 7, 2017 |
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Researchers
| F Aqlan | Aqlan, F | Researcher | | |
| M Makki | Makki, M | Researcher | | |
| R Abdel-Rahman | Abdel-Rahman, R | Researcher | | |
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