Document Details

Document Type : Article In Journal 
Document Title :
THE MECHANISM OF INHIBITION OF FATTY-ACID SYNTHASE BY THE HERBICIDE DIFLUFENICAN
THE MECHANISM OF INHIBITION OF FATTY-ACID SYNTHASE BY THE HERBICIDE DIFLUFENICAN
 
Document Language : Arabic 
Abstract : The bleaching herbicide diflufenican (N-(2,4-difluorophenyl)-2[3-(trifluoromethyl)-3-pyridine-carboxamide) carboxamide) has been shown to inhibit plant fatty acid synthase. The mechanism of this inhibition was studied further by measuring the activities of the reductase components of the Type II fatty acid synthase complexes from Escherichia coli and avocado (Persea americana) mesocarp. Diflufenican had no effect on beta-ketoacyl-ACP reductase activity, but competitively inhibited both NADH- and NADPH-dependent enoyl-ACP reductases. This result suggests that chemicals based on the diflufenican structure may be potential herbicides by virtue of their inhibition of fatty acid synthesis. 
Journal Name : PHYTOCHEMISTRY 
Volume : 35 
Issue Number : 3 
Publishing Year : 1994 AH  
Added Date : Saturday, June 14, 2008 

Researchers

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خالد بن عمر أبو النجا Researcher  

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